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충남대학교(약학사)
한국과학기술원(이학석사)
한국과학기술원(이학박사)
(2014-0976-01)Betulic acid의 eNOS 활성화를 통한 혈관보호효과에 대한 영향
(2013-2111)퇴행성뇌질환 공통병인을 표적으로 한 메탈로티오네인-III의 기능 연구
(2013-2084)아디포카인의 에스트라다이올 대사 조절에 의한 유방암 발병 신규 작용기전 연구
(2013-2073)약초 및 버섯의 항 알러지 활성 분석
(2013-1730)유해화학물질에 대한 연구실 안전사고 예방관리 시스템 개발
(2013-0191)담배연기 유해성분의 후성유전체 영향 연구
(2013-0034)학생인건비 약학대학 정혜광
(2012-2030)아디포카인의 에스트라다이올 대사 조절에 의한 유방암 발병 신규 작용기전 연구
(2012-0929)산양삼 유래 유용물질의 in vivo 아토피 개선 활성 연구
(2012-0928)산양삼 유래 유용물질 의 in vitro 아토피 개선 활성 연구
(2011-2058)마우스에서 와송추출물의 아토피 피부염 억제효과 분석
(2011-2038)아디포카인의 에스트라다이올 대사 조절에 의한 유방암 발병 신규 작용기전 연구
(2011-1774)산양삼 유래 유용물질의 암세포 전이 억제 기능성 연구
(2011-1773)산양삼 유래 유용물질의 신생혈관 조절 기능 연구
(2011-1277)구아바 천연물소재의 in vitro/ in vivo 아토피 피부염 억제 활성 검증
(2011-0757)천연물을 활용한 지방산 합성 효소 발현 조절 소재 개발
(2011-0444)자색고구마 안토시아닌의 항산화 건강기능식품의 개별인정 획득을 위한 기능성 검증
(2011-0222)장내미생물 배양법을 이용한 미생물 대사체 독성 평가 시험법 개발
(2011-0165)간세포에서 용존 산소량에 따른 알코올 대사 측정
(2010-1978)산양삼 유래 유용물질의 면역활성 기능성 연구
(2010-1977)산양삼 유래 유용물질의 항노화 및 항주름 기능성 연구
(2010-1452)구아바 천연물소재의 in vitro/ in vivo 아토피 피부염 억제 활성 검증
(2010-1069)길경와 갈근을 이용한 골 형성 촉진 및 골다공증 예방 기능성 식품 소재 개발
(2010-1015)자색고구마 안토시아닌 천연색소의 항산화 활성 검증
(2010-0663)피페린의 MMP-9의 발현 및 암세포 전이 억제
(2010-0583)새송이버섯 부산물을 이용한 아토피 피부염 억제 기능성 소재의 개발
(2010-0475)다년생도라지를 활용한 기관지염증 개선용 건강기능식품 개발
(2010-0187)자색고구마의 발효공정 최적화에 의한 천연 기능성색소 개발
(2010-0149)염증제어기술 기반 대사성질환 신약개발연구단
(2010-0133)산소 소주의 용존산소량에 따른 알코올 대사 효소 활성화 연구
(2010-0041)장내미생물 배양법을 이용한 미생물 대사체 독성 평가시험법 개발
(2009-2021)천연물소재의 in vitro / in vivo 아토피 피부염 억제 활성 검증
(2009-2020)자색고구마 안토시아닌 천연색소의 항산화 활성 검증
(2009-2017)천연물 유래 심혈관질환 개선 물질 발굴 및 치료 기술 개발
(2009-1998)발효자색고구마 추출물의 항비만 및 항당뇨
(2009-1991)메탈로치오네인의 암 전이와 신생혈관 형성에 대한 영향 및 기전 연구
(2009-1939)길경과 갈근을 이용한 골 형성 촉진 및 골다공증 예방 기능성 식품 소재 개발
(2009-1926)헛개나무 벌꿀을 이용한 간 기능보호 및 숙취에 도움이 되는 기능성 식품소재 개발 및 제품화
(2009-1925)새송이버섯 부산물을 이용한 아토피 피부염 억제 기능성 소재의 개발
(2009-1924)다년생 도라지를 활용한 기관지염증 개선용 건강기능식품 개발
(2009-1896)메탈로치오네인의 암 전이와 신생혈관 형성에 대한 영향 및 기전 연구
(2009-1884)어성초와 길경을 이용한 알러지 억제 및 제어 기능성 식품 소재 개발
(2009-1828)장내미생물 배양법을 이용한 미생물 대사체 독성 평가시험법 개발
- Protective mechanisms of 3-caffeoyl, 4-dihydrocaffeoyl quinic acid from Salicornia herbacea against tert-butyl hydroperoxide-induced oxidative damage
- Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase
- Immunotoxicological Investigation of 1-furan-2-yl-3-pyridin-2-yl-propenone in Female BALB/c Mice
- Metallothionein-III Provides Neuronal Protection through Activation of Nuclear Factor-kappa B via the TrkA/Phosphatidylinositol-3 kinase/Akt Signaling Pathway
- Novel Role of Pin1 Induction in Type II Collagen-Mediated Rheumatoid Arthritis
- Nephrotoxic Potential and Toxicokinetics of Tetrabromobisphenol a in Rat for Risk Assessment
- Risk Assessment of Tetrabromobisphenol a on Cyclooxygenase-2 Expression Via Map Kinase/NF-kappa B/AP-1 Signaling Pathways in Murine Macrophages
- Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium
- Tetrabromobisphenol-A가 처리된 랫드의 간에서 항산화활성 평가
- Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells
- Dihydro-N-caffeoyltyramine down-regulates cyclooxygenase-2 expression by inhibiting the activities of C/EBP and AP-1 transcription factors
- Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-kappa B-dependent MMP-9 expression
- Inhibitory effect of 3-caffeoyl-4-dicaffeoylquinic acid from Salicornia herbacea against phorbol ester-induced cyclooxygenase-2 expression in macrophages
- Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells
- Prostaglandin E-2 Induces CYP1B1 Expression via Ligand-Independent Activation of the ER alpha Pathway in Human Breast Cancer Cells
- Molecular mechanism of endothelial nitric-oxide synthase activation by Platycodon grandiflorum root-derived saponins
- Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKC alpha/Raf/MAPKs and NF-kappa B/AP-1-dependent mechanisms
- Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase C alpha-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated kinase/activator protein-1
- Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by bergamottin via the inhibition of protein kinase C delta/p38 mitogen-activated protein kinase and JNK/nuclear factor-kappa B-dependent matrix metalloproteinase-9 expression
- Molecular mechanism of suppression of MDR1 by puerarin from Pueraria lobata via NF-kappa B pathway and cAMP-responsive element transcriptional activity-dependent up-regulation of AMP-activated protein kinase in breast cancer MCF-7/adr cells
- Hepatotoxicity and Immunotoxicity of 1-Bromohexane and Its Glutathione Conjugation in Female BALB/c Mice
- Oxygenated Alcohol - Sober Faster!
- 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression
- The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells
- Upregulation of Cyclooxygenase-2 by 4-Nonylphenol is Mediated Through the Cyclic Amp Response Element Activation Pathway
- Role of Metabolism In 1-Bromopropane-Induced Hepatotoxicity in Mice
- Anti-fibrotic effects of the anthocyanins isolated from the purple-fleshed sweet potato on hepatic fibrosis induced by dimethylnitrosamine administration in rats
- Saponins from the roots of Platycodon grandiflorum stimulate osteoblast differentiation via p38 MAPK- and ERK-dependent RUNX2 activation
- Anthocyanins isolated from the purple-fleshed sweet potato attenuate the proliferation of hepatic stellate cells by blocking the PDGF receptor
- The flavonoids apigenin and luteolin suppress ultraviolet A-induced matrix metalloproteinase-1 expression via MAPKs and AP-1-dependent signaling in HaCaT cells
- Ethyl acetate extract of Psidium guajava inhibits IgE-mediated allergic responses by blocking Fc epsilon RI signaling
- Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression
- Metallothionein-2A overexpression increases the expression of matrix metalloproteinase-9 and invasion of breast cancer cells
- Metformin inhibits P-glycoprotein expression via the NF-kappa B pathway and CRE transcriptional activity through AMPK activation
- Suppression of EGF-induced tumor cell migration and matrix metalloproteinase-9 expression by capsaicin via the inhibition of EGFR-mediated FAK/Akt, PKC/Raf/ERK, p38 MAPK, and AP-1 signaling
- Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKC alpha/ERK1/2-dependent matrix metalloproteinase-9 expression
- Role of Metabolism by Intestinal Bacteria in Arbutin-induced Toxicity In Vitro
- Inhibitory effect of Pleurotus eryngii extracts on the activities of allergic mediators in antigen-stimulated mast cells
- Xanthohumol from the hop plant stimulates osteoblast differentiation by RUNX2 activation
- Acteoside inhibits PMA-induced matrix metalloproteinase-9 expression via CaMK/ERK- and JNK/NF-kappa B-dependent signaling
- N-Acetylglucosamine suppress collagenases activation in ultraviolet B-irradiated human dermal fibroblasts: Involvement of calcium ions and mitogen-activated protein kinases
- MolecularMechanismofTetrabromobisphenolA(TBBPA)-inducedTarget Organ Toxicity in Sprague-Dawley Male Rats
- Protective mechanisms of anthocyanins from purple sweet potato against tert-butyl hydroperoxide-induced hepatotoxicity
- Inhibition of acrolein-stimulated MUC5AC expression by Platycodon grandiflorum root-derived saponin in A549 cells
- Psidium guajava extract inhibits thymus and activation-regulated chemokine (TARC/CCL17) production in human keratinocytes by inducing heme oxygenase-1 and blocking NF-kappa B and STAT1 activation
- Role of metabolism by the human intestinal microflora in arbutin-induced cytotoxicity in HepG2 cell cultures
- CCAAT/enhancer-binding protein beta activation by capsaicin contributes to the regulation of CYP1A1 expression, mediated by the aryl hydrocarbon receptor
- Saponins from the roots of Platycodon grandiflorum suppress ultraviolet A-induced matrix metalloproteinase-1 expression via MAPKs and NF-kappa B/AP-1-dependent signaling in HaCaT cells
- Puerarin activates endothelial nitric oxide synthase through estrogen receptor-dependent PI3-kinase and calcium-dependent AMP-activated protein kinase
- Purple sweet potato anthocyanins attenuate hepatic lipid accumulation through activating adenosine monophosphate-activated protein kinase in human HepG2 cells and obese mice
- Role of Metabolism by Intestinal Bacteria in Arbutin-Induced Suppression of Lymphoproliferative Response in vitro
- Role of metabolism by human intestinal microflora in geniposide-induced toxicity in HepG2 cells
- Platycodi Radix suppresses development of atopic dermatitis-like skin lesions
- Biotransformation of geniposide by human intestinal microflora on cytotoxicity against HepG2 cells
- Anti-inflammatory effect of sweetfish-derived protein and its enzymatichydrolysate on LPS-induced RAW264.7 cells via inhibition of NF-kappa B transcription
- Protective role of intestinal bacterial metabolism against baicalin-induced toxicity in HepG2 cell cultures
- The coffee diterpene kahweol inhibits metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation
- 1-Bromopropane up-regulates cyclooxygenase-2 expression via NF-kappa B and C/EBP activation in murine macrophages
- Capsaicin induces CYP3A4 expression via pregnane X receptor and CCAAT/enhancer-binding protein beta activation
- Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-kappa B, C/EBP and AP-1 signaling pathways in murine macrophages
- Cultivated ginseng suppresses ultraviolet B-induced collagenase activation via mitogen-activated protein kinases and nuclear factor kappa B/activator protein-1-dependent signaling in human dermal fibroblasts
- Inhibitory effect of Psidium guajava water extract in the development of 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice
- Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures
- Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling
- Role of intestinal microflora in xenobiotic-induced toxicity
- Topical application of Pleurotus eryngii extracts inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice by the regulation of Th1/Th2 balance
- Saponins, especially platycodin D, from Platycodon grandiflorum modulate hepatic lipogenesis in high-fat diet-fed rats and high glucose-exposed HepG2 cells
- Mollugin inhibits proliferation and induces apoptosis by suppressing fatty acid synthase in HER2-overexpressing cancer cells
- 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea attenuates high glucose-induced hepatic lipogenesis in human HepG2 cells through activation of the liver kinase B1 and silent information regulator T1/AMPK-dependent pathway
- Inhibitory effect of dihydroartemisinin against phorbol ester-induced cyclooxygenase-2 expression in macrophages
- Saponins from Platycodon grandiflorum inhibit hepatic lipogenesis through induction of SIRT1 and activation of AMP-activated protein kinase in high-glucose-induced HepG2 cells
- Cultivated ginseng inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice and TNF-alpha/IFN-gamma-induced TARC activation in HaCaT cells
- Platycodi Radix attenuates dimethylnitrosamine-induced liver fibrosis in rats by inducing Nrf2-mediated antioxidant enzymes
- Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells
- Glycogen synthase kinase 3 alpha phosphorylates and regulates the osteogenic activity of Osterix
- S-Allyl cysteine attenuates free fatty acid-induced lipogenesis in human HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway
- Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways
- The effect of gut microbiota on drug metabolism
- Simultaneous Determination of Olanzapine and its Major Metabolite N-Desmethyl Olanzapine in Rat Plasma by HPLC-MS/MS; Application of PK in Rat
- Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells
- Anti-diabetic and anti-inflammatory effect of a novel selective 11 beta-HSD1 inhibitor in the diet-induced obese mice
- Anti-Inflammatory Activities of Methanol Extract of Mastixia arborea CB Clarke as to Mouse Macrophage and Paw Edema
- Genipin induces cyclooxygenase-2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in RAW 264.7 cells
- Saponins from the roots of Platycodon grandiflorum suppresses TGFb1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells
- Bromopropane compounds inhibit osteogenesis by ERK-dependent Runx2 inhibition in C2C12 cells
- Role of metabolism by intestinal microbiota in pharmacokinetics of oral baicalin
- Leptin induces CYP1B1 expression in MCF-7 cells through ligand-independent activation of the ERα pathway.
- Protective Effects of Diallyl Sulfide against Thioacetamide-Induced Toxicity: A Possible Role of Cytochrome P450 2E1
- Inhibitory effects of Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF- B and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1
- Metallothionein-III increases ADAM10 activity in association with furin, PC7, and PKCa during non-amyloidogenic processing
- 예방약학
- 예방약학
- 건강기능식품학
- 보건약학
- 자색고구마 추출물을 함유하는 간섬유증 예방 및 치료용 조성물
- 장생도라지 유래의 조사포닌 분획물을 함유하는 골다공증 예방 및 치료용 조성물
- 3-카페오일-4-다이하이드로카페오일 퀴닉산을 함유하는 암 전이 억제용 약학 조성물
- 신규 쿠마린 유도체 및 이를 함유하는 항염증, 항알러지용조성물 (Novel coumarin derivatives and the composition comprising the same showing anti-inflammatory and anti-allergy activity)
- 구아바로부터 항균활성 물질의 수득방법과 그 항균활성 물질을 포함하는 아토피 피부염, 무좀, 대장균 감염 억제용 조성물 (Method for obtaining antibacterial substance from guava and uses of the substance)
- 새송이버섯 추출물을 함유하는 아토피 피부염의 예방 또는
- 잔토휴몰을 함유하는 골다공증 예방 및 치료용 조성물
- 뱀딸기의 에틸아세테이트분획물 및 이를 유효성분으로포함하는 알러지 치료용 약학적 조성물
- 자색고구마알갱이음료의제조방법(MANUFACTURINGMETHODFORPURPLESWEETPOTATOGRAIN DRINK)
- 장생도라지유래의조사포닌분획물을함유하는골다공증예방및치료용조성물(Acompositioncomprisingcrudesaponinfractionfrom old platycodon for treating and preventing osteoporosis)
- 자색고구마추출물을함유하는간섬유증예방및치료용조성물(Acompositioncomprisingextractofpurple-fleshed sweet potato for treating and preventing hepatic fibrosis)
- 자색고구마추출물발효액을유효성분으로함유하는지방생성및축적저해용조성물(Compositionforinhibitingdifferentiationand accumulation of fat cells comprising fermented extract of purple sweet potato as an active ingredient)
- 몰루긴을함유하는유방암또는난소암의예방또는치료용조성물(Acompositioncomprisingmolluginfortreatingor preventing breast and ovary cancer)
- 몰루긴을 함유하는 항암용 조성물(A composition comprising mollugin for treating cancer)
- 잔토휴몰을함유하는골다공증예방및치료용조성물(Acompositioncomprisingxanthohumolfortreatingand preventing osteoporosis)
- 3-카페오일-4-다이하이드로카페오일퀴닉산을함유하는암전이억제용약학조성물(Apharmaceuticalcompositioncomprising 3-caffeoyl-4-dihydrocaffeoylquinic acid for inhibiting cancer metastasis)
- 새송이버섯추출물을함유하는아토피피부염의예방또는치료용조성물(AcompositioncomprisingextractofPleurotuseryngii for treating or preventing atopic dermatitis)
- 티아닌을함유하는기관지염의예방또는치료용조성물(Acompositioncomprisingtheaninefortreatingor preventing bronchitis)